Soft tissue and hard tissue engineering in oral and maxillofacial surgery.
Identifieur interne : 008174 ( Main/Exploration ); précédent : 008173; suivant : 008175Soft tissue and hard tissue engineering in oral and maxillofacial surgery.
Auteurs : Rainer Schmelzeisen [Allemagne] ; Ronald Schimming ; Michael SittingerSource :
- Annals of the Royal Australasian College of Dental Surgeons [ 0158-1570 ] ; 2002.
Descripteurs français
- KwdFr :
- Acide polyglycolique (), Humains, Ingénierie tissulaire (), Matériaux biocompatibles (), Maxillaire (), Mâchoire partiellement édentée (), Ostéoblastes (physiologie), Ostéogenèse (physiologie), Polyesters (), Procédures de chirurgie maxillofaciale et buccodentaire, Procédures orthopédiques, Projets pilotes, Prélèvement d'organes et de tissus, Périoste (cytologie), Reconstruction de crête alvéolaire (), Trame osseuse (physiologie), Trame osseuse (transplantation), Transplantation osseuse ().
- MESH :
- cytologie : Périoste.
- physiologie : Ostéoblastes, Ostéogenèse, Trame osseuse.
- Acide polyglycolique, Humains, Ingénierie tissulaire, Matériaux biocompatibles, Maxillaire, Mâchoire partiellement édentée, Polyesters, Procédures de chirurgie maxillofaciale et buccodentaire, Procédures orthopédiques, Projets pilotes, Prélèvement d'organes et de tissus, Reconstruction de crête alvéolaire, Trame osseuse, Transplantation osseuse.
English descriptors
- KwdEn :
- Alveolar Ridge Augmentation (methods), Biocompatible Materials (chemistry), Bone Matrix (physiology), Bone Matrix (transplantation), Bone Transplantation (methods), Humans, Jaw, Edentulous, Partially (surgery), Maxilla (surgery), Oral Surgical Procedures, Orthopedic Procedures, Osteoblasts (physiology), Osteogenesis (physiology), Periosteum (cytology), Pilot Projects, Polyesters (chemistry), Polyglycolic Acid (chemistry), Tissue Engineering (methods), Tissue and Organ Harvesting.
- MESH :
- chemical , chemistry : Biocompatible Materials, Polyesters, Polyglycolic Acid.
- cytology : Periosteum.
- methods : Alveolar Ridge Augmentation, Bone Transplantation, Tissue Engineering.
- physiology : Bone Matrix, Osteoblasts, Osteogenesis.
- surgery : Jaw, Edentulous, Partially, Maxilla.
- transplantation : Bone Matrix.
- Humans, Oral Surgical Procedures, Orthopedic Procedures, Pilot Projects, Tissue and Organ Harvesting.
Abstract
Autologous, allogenic and alloplastic materials for bony reconstruction in the cranio-maxillofacial area have specific drawbacks, thus stimulating the ongoing search for new (bio-) materials. Cultivated skin and mucosa grafts are in routine clinical use in head and neck reconstruction but so far, to the best of our knowledge, no successful clinical application has been described of periosteum-derived tissue-engineered bone for augmentation of the edentulous posterior maxilla. In a pilot clinical study, augmentation of the posterior maxilla was carried out using a bone matrix derived from mandibular periosteum cells on an Ethisorb fleece. In this paper we demonstrate the fabrication of the matrix, its clinical application, and histological results in two patients. Our results suggest that periosteum-derived osteoblasts on a suitable matrix can form lamellar bone within four months after transplantation and provide a reliable basis for implant insertion.
PubMed: 14507132
Affiliations:
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Le document en format XML
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<term>Biocompatible Materials (chemistry)</term>
<term>Bone Matrix (physiology)</term>
<term>Bone Matrix (transplantation)</term>
<term>Bone Transplantation (methods)</term>
<term>Humans</term>
<term>Jaw, Edentulous, Partially (surgery)</term>
<term>Maxilla (surgery)</term>
<term>Oral Surgical Procedures</term>
<term>Orthopedic Procedures</term>
<term>Osteoblasts (physiology)</term>
<term>Osteogenesis (physiology)</term>
<term>Periosteum (cytology)</term>
<term>Pilot Projects</term>
<term>Polyesters (chemistry)</term>
<term>Polyglycolic Acid (chemistry)</term>
<term>Tissue Engineering (methods)</term>
<term>Tissue and Organ Harvesting</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Acide polyglycolique ()</term>
<term>Humains</term>
<term>Ingénierie tissulaire ()</term>
<term>Matériaux biocompatibles ()</term>
<term>Maxillaire ()</term>
<term>Mâchoire partiellement édentée ()</term>
<term>Ostéoblastes (physiologie)</term>
<term>Ostéogenèse (physiologie)</term>
<term>Polyesters ()</term>
<term>Procédures de chirurgie maxillofaciale et buccodentaire</term>
<term>Procédures orthopédiques</term>
<term>Projets pilotes</term>
<term>Prélèvement d'organes et de tissus</term>
<term>Périoste (cytologie)</term>
<term>Reconstruction de crête alvéolaire ()</term>
<term>Trame osseuse (physiologie)</term>
<term>Trame osseuse (transplantation)</term>
<term>Transplantation osseuse ()</term>
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<term>Polyesters</term>
<term>Polyglycolic Acid</term>
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<term>Bone Transplantation</term>
<term>Tissue Engineering</term>
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<term>Ostéogenèse</term>
<term>Trame osseuse</term>
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<term>Osteoblasts</term>
<term>Osteogenesis</term>
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<term>Maxilla</term>
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<keywords scheme="MESH" qualifier="transplantation" xml:lang="en"><term>Bone Matrix</term>
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<term>Oral Surgical Procedures</term>
<term>Orthopedic Procedures</term>
<term>Pilot Projects</term>
<term>Tissue and Organ Harvesting</term>
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<term>Ingénierie tissulaire</term>
<term>Matériaux biocompatibles</term>
<term>Maxillaire</term>
<term>Mâchoire partiellement édentée</term>
<term>Polyesters</term>
<term>Procédures de chirurgie maxillofaciale et buccodentaire</term>
<term>Procédures orthopédiques</term>
<term>Projets pilotes</term>
<term>Prélèvement d'organes et de tissus</term>
<term>Reconstruction de crête alvéolaire</term>
<term>Trame osseuse</term>
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<front><div type="abstract" xml:lang="en">Autologous, allogenic and alloplastic materials for bony reconstruction in the cranio-maxillofacial area have specific drawbacks, thus stimulating the ongoing search for new (bio-) materials. Cultivated skin and mucosa grafts are in routine clinical use in head and neck reconstruction but so far, to the best of our knowledge, no successful clinical application has been described of periosteum-derived tissue-engineered bone for augmentation of the edentulous posterior maxilla. In a pilot clinical study, augmentation of the posterior maxilla was carried out using a bone matrix derived from mandibular periosteum cells on an Ethisorb fleece. In this paper we demonstrate the fabrication of the matrix, its clinical application, and histological results in two patients. Our results suggest that periosteum-derived osteoblasts on a suitable matrix can form lamellar bone within four months after transplantation and provide a reliable basis for implant insertion.</div>
</front>
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<tree><noCountry><name sortKey="Schimming, Ronald" sort="Schimming, Ronald" uniqKey="Schimming R" first="Ronald" last="Schimming">Ronald Schimming</name>
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<country name="Allemagne"><noRegion><name sortKey="Schmelzeisen, Rainer" sort="Schmelzeisen, Rainer" uniqKey="Schmelzeisen R" first="Rainer" last="Schmelzeisen">Rainer Schmelzeisen</name>
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